- Chantix – Adverse Events Defined in simple terms:
Abdominal Pain- tummy hurts in upper, lower, tender or distension, stomach discomfort
Flatulence - farting, passing gas, breaking wind
Dyspepsia- hard or difficult digestion; can include bloating, belching, feeling fullness in tummy
Gastroesophageal reflux disease- acid from stomach coming up as far as throat
Insomnia- unable to sleep; includes initial, middle and early morning awakening (counted once in table)
Abnormal Dreams- unusual dreams, vivid, wild, realistic yet not REAL (nightmares for some)
Dysgeusia- distortion or decrease in the sense of taste
Somnolence- state of near-sleep, a strong desire to sleep, sleeping for long periods
Lethargy- drowsiness or aversion to activity
Fatigue/Malaise/Asthenia- tired; out of sorts / general feeling of being unwell; lacks strength/weakness
Rhinorrhea- runny nose
Dyspnoea/Dyspnea- shortness of breath, is perceived difficulty breathing or painful breathing
Upper Respiratory Tract Disorder- problems with nostril, nasal cavity, throat, mouth and voice box
Pruritis- an itch, a sensation on the skin that causes the desire to scratch
Anorexia- an eating disorder where people starve themselves
Lymphadenopathy- disease of the lymph nodes
Leukocytosis- an elevation of the white blood cell count above the normal range
Thrombocytopenia- the presence of relatively few platelets in blood
Splenomegaly- enlargement of the spleen; usually associated with increased workload
Angina pectoris- chest pain due to lack of blood and hence oxygen supply of the heart muscle
Arrhythmia- an irregular heartbeat
Bradycardia- a resting heart rate of fewer than 60 beats per minute
Ventricular extrasystoles- a form of irregular heatbeat; premature contractions of the heart chamber
Myocardial infarction- heart attack
Palpitations- an awareness of heartbeat; shaking motion of the heart muscle
Tachycardia- a form of rapid heartbeat usually in excess of 100 beats per minute
Atrial fibrillation- abnormal heart rhythm (afib) that involves the two upper chambers of the heart
Cardiac flutter- similar to above (afib)
Coronary artery disease- occurs when the arteries that supply the heart become hardened and narrowed
Cor pulmonale- right heart failure – because of respiratory disorder
Acute coronary syndrome- a set of signs or symptoms interpreted because of decreased blood flow
Tinnitus- a ringing I n the ears caused from damage to the nerve endings
Vertigo- a type of dizziness that is characterized by the sensation of spinning
Meniere’s disease- a disorder of the inner ear that can affect hearing and balance
Thyroid gland disorders- a gland that regulates the body’s metabolism; it produces hormones
Conjuntivitis- inflammation of the membrane that covers the interiors of the eyelids
Cataract subcapsular- the back of the membrane that envelopes the lens; a milky white fluid of the lens
Ocular vascular disorder- a type of vision loss
Photophobia- an experience of pain to the eyes due to light exposure
Vitreous floaters- the clear fluid between the lens and the retina of the eyeball with deposits floating
Diarrhea- frequent watery loose, bowel movements
Gingivitis- inflammation of the gums around the teeth
Dysphagia- difficulty swallowing
Enterocolitis- an inflamtion of the large and small intestines
Erucation- fast nausea combined with burdensome headaches
Gastritis- inflammation of the stomach lining
Gastrointestinal hemorrhage- bleeding in the gastrointestinal tract
Mouth ulceration- open sores in the mouth
Esophagitis- inflamtion of the tube that carries food from the throat to the stomach
Gastriculcer- open sore in the stomach
Pancreatitis acute- rapid inflammation of the gland organ in the digestive system
Edema- swelling of any organ
Pyrexia- fever; abnormal elevation of body temperature
Hypersensitivity- undesirable reactions produced by the normal immune system
Drug hypersensitivity- an adverse drug reaction; ACAAI estimated deaths of 106,000 a year and rising
Electrocardiogram abnormal- abnormal ECG or EKG
Diabetes mellitus- a syndrome characterized by disordered metabolism and high blood sugar
Hyperlipidemia- the presence of high amounts of fatty molecules in the blood
Hypokalemia- a potentially fatal condition in which the body fails to retain sufficient potassium to maintain health
Hyperkalemia- high levels of potassium that can cause heart attacks
Hypoglycemia- low levels of glucose (sugar) in the blood; aka “brain fuel”
Arthralgia- joint pain; or an allergic reaction to medication
Musculoskeletal pain- pain in the organ system that gives animals the ability to physically move
Myalgia- muscle pain
Osteoporosis- reduced bone mineral density
Myositis- inflammation of the muscles; likely to be cause by autoimmune conditions vs infection (autoimmunity- is the failure of an organism to recognize its own constituent parts (down to the sub-molecular levels) as “self”, which result in an immune response against its own cells and tissues. Examples: multiple sclerosis (MS), diabetes mellitus
Amnesia- a condition in which memory is disturbed; causes can be organic or functional
Migraine- is a neurological disease
Parosmia- a disorder of sense of smell when an odor is actually present, but incorrectly perceived
Psychomotor hyperactivity- of or relating to motor action directly proceeding from mental activity; hyper- really exited; hypo- less then normal
Syncope- transient loss of consciousness; blackouts; fainting; altered conciousness
Cerebrovascular accident- stroke is the clinical designation for a rapidly developing loss of brain function due to an interruption in blood supply to all or part of the brain
Dysarthria- speech impairment; is difficult, poorly pronounced speech, such as slurring; inability to speak
Facial palsy- aka Bell’s palsy is characterized by the face muscles drooping on the effected side
Multiple sclerosis- a disease of the nervous system in which the myelin sheath of the neurons is damaged
Nystagmus- involuntary eye movement that can be part of reflex eye movement
Psychomotor skills impaired- sleep deprivation results in poor motor skills from mental activity
Transient ischemic attack- mini stroke
Visual field defect- a blind spot within the normal field of vision
Libido decrease- low sexual desire
Bradyphrenia- a slowing of thought processes
Euphoric mood- an extremely happy mood
Psychotic disorder- mental illness that centers around abnormal thinking and perceptions
Suicidal ideation- a common medical term for thoughts about suicide (taking your life)
Polyuria- passing large amounts of urine
Nephrolithiasis- kidney stones; solid creations of dissolved minerals in urine
Nocturia- is the need to get up during the night to urinate
Urethral syndrome- a female syndrome (signs/symptoms) urinary frequent, urgency, burning & more
Renal failure acute- a rapid loss of kidney function
Urinary retention- a lack of the ability to urinate
Menstrual disorder- an irregular condition in a woman’s monthly cycle
Eretile dysfunction- the inability to develop or maintain and erection of the penis; sexual dysfunction
Sexual dysfunction- difficulty during any stage of the sexual act that prevents enjoyment (arousal, orgasm or resolution)
Epistaxis- nose bleeds
Asthma- a chronic disease that affect your airways
Pleurisy- an inflammation of the membrane, cavity surrounding the lungs
Pulmonary embolism- a blockage of the arteries that carry blood to the lungs
Hyperhidrosis- excessive sweating
Dermatitus- inflammation of the skin as an allergic reaction
Eczema- inflammation upper layers of the skin as an allergic reaction
Erythema- a large abnormal redness of the skin caused by capillary congestion; a sign of inflammation
Psoriasis- scaly red patch on the skin and joints
Urticaria- or hives; a skin condition usually due to allergies; raised red welts; needle rash; drug reactions
Photosensitivity reaction- more sensitive than normal to light
Hypertension- high blood pressure
Hypotension- low blood pressure,
Peripheral ischemia- a condition that low blood supply to the limbs causes cramping and chronic pain
Thrombosis- the formation of a clot inside a blood vessel blocking the flow of blood
Other adverse effects: Nausea, vomiting, constipation, dry mouth, nightmare, headache, rash, increased appetite, decreased appetite, anemia, eye irritation, vision blurred, visual disturbance, eye pain, acquired night blindness, blindness transient, chest pain, influenza like illness, thirst, chest discomfort, chills, weigh increase, back pain, muscle cramp, disturbance in attention, dizziness, sensory disturbance, tremor, balance disorder, convulsion, anxiety, emotional disorder, irritability, restlessness, aggression, agitation, disorientation, dissociation, thinking abnormal, hallucination, urine abnormal, respiratory disorders, acne, dry skin.